Detalhe da pesquisa
1.
The emerging landscape of single-molecule protein sequencing technologies.
Nat Methods
; 18(6): 604-617, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099939
2.
Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p.
Nucleic Acids Res
; 50(2): 1017-1032, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34908151
3.
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy.
Pharm Res
; 40(6): 1373-1382, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36195820
4.
Selective C-Terminal Conjugation of Protease-Derived Native Peptides for Proteomic Measurements.
Langmuir
; 38(30): 9119-9128, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35856835
5.
Grand Challenges in Pharmaceutical Research Series: Ridding the Cold Chain for Biologics.
Pharm Res
; 38(1): 3-7, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33555493
6.
Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation.
J Biomol NMR
; 74(10-11): 643-656, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32700053
7.
Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional 1H,13C Methyl NMR Methods for Characterization of the Higher Order Structure of IgG1 Monoclonal Antibodies.
Anal Chem
; 92(9): 6366-6373, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32267681
8.
Best Practices in Utilization of 2D-NMR Spectral Data as the Input for Chemometric Analysis in Biopharmaceutical Applications.
J Chem Inf Model
; 60(4): 2339-2355, 2020 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32249579
9.
Leveraging nature's biomolecular designs in next-generation protein sequencing reagent development.
Appl Microbiol Biotechnol
; 104(17): 7261-7271, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32617618
10.
Chemometric Outlier Classification of 2D-NMR Spectra to Enable Higher Order Structure Characterization of Protein Therapeutics.
Chemometr Intell Lab Syst
; 1992020.
Artigo
em Inglês
| MEDLINE | ID: mdl-34135539
11.
Engineering ClpS for selective and enhanced N-terminal amino acid binding.
Appl Microbiol Biotechnol
; 103(6): 2621-2633, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30675637
12.
Selective suppression of excipient signals in 2D 1H-13C methyl spectra of biopharmaceutical products.
J Biomol NMR
; 72(3-4): 149-161, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30483914
13.
A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res
; 44(13): 6232-41, 2016 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27141962
14.
Multivariate Analysis of Two-Dimensional 1H, 13C Methyl NMR Spectra of Monoclonal Antibody Therapeutics To Facilitate Assessment of Higher Order Structure.
Anal Chem
; 89(21): 11839-11845, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28937210
15.
A Molecular Model for Lithium's Bioactive Form.
Biophys J
; 111(2): 294-300, 2016 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27463132
16.
Excipient Innovation Through Precompetitive Research.
Pharm Res
; 38(12): 2179-2184, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931284
17.
2D (1)H(N), (15)N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies.
Pharm Res
; 33(2): 462-75, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26453189
18.
Mapping monoclonal antibody structure by 2D 13C NMR at natural abundance.
Anal Chem
; 87(7): 3556-61, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728213
19.
TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses.
Blood
; 122(11): 1935-45, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23908469
20.
Molecular determinants of HIV-1 NCp7 chaperone activity in maturation of the HIV-1 dimerization initiation site.
Nucleic Acids Res
; 41(4): 2565-80, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275531